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Publications by Iolanda Micco

Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach

Chemical Biology and Drug Design
BiochemistryOrganic ChemistryDrug DiscoveryMolecular MedicinePharmacology
2014English

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Affinity-Based Screening of MDM2/MDMX–p53 Interaction Inhibitors by Chemical Array: Identification of Novel Peptidic Inhibitors

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2013English

Synthesis of Cell-Permeable Stapled Peptide Dual Inhibitors of the P53-Mdm2/MDMX Interactions via Photoinduced Cycloaddition

Bioorganic and Medicinal Chemistry Letters
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A Dimethylbromobenzene-Cysteine Stapled Peptide Dual Inhibitor of the P53-Mdm2/MDMX Interactions

Hepatoma Research
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MdmX Protects P53 From Mdm2-Mediated Degradation

Molecular and Cellular Biology
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2000English

Targeting P53-Mdm2-MDMX Loop for Cancer Therapy

Sub-Cellular Biochemistry
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Human Epidermal Growth Factor Receptor 4 (Her4) Suppresses P53 Protein via Targeting the MDMX-MDM2 Protein Complex

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
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Structures of Low Molecular Weight Inhibitors Bound to MDMX and MDM2 Reveal New Approaches for P53-MDMX/Mdm2 Antagonist Drug Discovery

Cell Cycle
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P53 Regulation: Teamwork Between RING Domains of Mdm2 and MdmX

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
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Stochastic Modeling and Simulation of the P53-Mdm2/MDMX Loop

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GeneticsMolecular BiologyComputational TheorySimulationComputational MathematicsMathematicsModeling
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