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Publications by John E Burke
Allosteric Activation of PI3Kα By Oncogenic Mutations
Oncotarget
Oncology
Activation of Phospholipase C Β by Gβγ and Gαq Involves C-Terminal Rearrangement to Release Auto-Inhibition
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Allosteric Regulation of Vinculin Activation by Alpha-Actinin
Biophysical Journal
Biophysics
Activation of the EGF Receptor by Ligand Binding and Oncogenic Mutations: The “Rotation Model”
Cells
Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2
Cancer Cell
Cancer Research
Oncology
Cell Biology
Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability
Discovery of Bifunctional Oncogenic Target Inhibitors Against Allosteric Mitogen-Activated Protein Kinase (MEK1) and Phosphatidylinositol 3Kinase (PI3K)
Activation of PI3K by Ras: Single Molecule Studies of the Activation Mechanism
Biophysical Journal
Biophysics
Technique Pinpoints Oncogenic BRCA1 Mutations
Cancer Discovery
Oncology
Oncogenic Function of P34SEI-1 via NEDD4-1-mediated PTEN Ubiquitination/Degradation and Activation of the PI3K/AKT Pathway
International Journal of Oncology
Cancer Research
Oncology
Oncogenic Mutations Mimic and Enhance Dynamic Events in the Natural Activation of Phosphoinositide 3-Kinase P110 (PIK3CA)
Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
