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Publications by Nobuo Machinaga

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

Translational Vision Science and Technology
OphthalmologyBiomedical Engineering
2018English

A Novel Synthetic Approach to Very Late Antigen-4 Antagonist Trans-4-[1-[[2,5-Dichloro-4-(1-Methyl-3-Indolylcarboxyamide)phenyl]acetyl]-(4s)-Methoxy-(2s)-Pyrrolidinylmethoxy]cyclohexanecarboxylic Acid via Tert-Butyl Trans-[(4s)-Methoxy-(2s)-Pyrrolidinylmethoxy]cyclohexanecarboxylate as a Key Intermediate

Chemical and Pharmaceutical Bulletin
MedicineDrug DiscoveryChemistry
2011English

A Concise Synthesis of a Very Late Antigen-4 Antagonist Trans-4-[1-[[2,5-Dichloro-4-(1-Methyl-3-Indolylcarboxyamide)phenyl]acetyl]-(4s)-Methoxy-(2s)-Pyrrolidinylmethoxy]cyclohexanecarboxylic Acid via Reductive Etherification

Chemical and Pharmaceutical Bulletin
MedicineDrug DiscoveryChemistry
2012English

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