Discover open access scientific publications

Search, annotate, share and cite publications

Publications by P. Jeffrey Conn

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

Annual Review of Pharmacology and Toxicology
ToxicologyPharmacology
2010English

M1-Positive Allosteric Modulators Lacking Agonist Activity Provide the Optimal Profile for Enhancing Cognition

Neuropsychopharmacology
PsychiatryMental HealthPharmacology
2018English

Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators

ACS Chemical Biology
BiochemistryMedicineMolecular Medicine
2016English

Targeting Metabotropic Glutamate Receptors for Novel Treatments of Schizophrenia

Molecular Brain
Molecular NeuroscienceMolecular BiologyCellular
2017English

The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia

Journal of NeuroImmune Pharmacology
NeuroscienceAllergyImmunologyPharmacology
2016English

Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4)

Journal of Biomolecular Screening
Molecular MedicinePharmacologyBiochemistryAnalytical ChemistryBiotechnologyDrug Discovery
2015English

Development of Novel M1 Antagonist Scaffolds Through the Continued Optimization of the MLPCN Probe ML012

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2012English

Further Optimization of the M5 NAM MLPCN Probe ML375: Tactics and Challenges

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2015English

Chemical Lead Optimization of a Pan Gq mAChR M1, M3, M5 Positive Allosteric Modulator (PAM) Lead. Part I: Development of the First Highly Selective M5 PAM

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Heterobiaryl and Heterobiaryl Ether Derived M5 Positive Allosteric Modulators

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2025 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy