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Publications by Patrick M. Sexton
Cryo-Em Structure of the Active, Gs-Protein Complexed, Human CGRP Receptor
Nature
Multidisciplinary
Β-Arrestin-Biased Agonists of the GLP-1 Receptor From Β-Amino Acid Residue Incorporation Into GLP-1 Analogues
Journal of the American Chemical Society
Biochemistry
Colloid
Catalysis
Chemistry
Surface Chemistry
Structural Determinants of Allosteric Agonism and Modulation at the M4Muscarinic Acetylcholine Receptor
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Second Extracellular Loop of Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Differentially Regulates Orthosteric but Not Allosteric Agonist Binding and Function
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Identification of Orthosteric and Allosteric Site Mutations in M2Muscarinic Acetylcholine Receptors That Contribute to Ligand-Selective Signaling Bias
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity Across the Receptor Homodimeric Complex
Journal of Medicinal Chemistry
Drug Discovery
Molecular Medicine
Structural Basis for Modulation of a GPCR by Allosteric Drugs
Biophysical Journal
Biophysics
Molecular Basis of Action of a Small Molecule Positive Allosteric Modulator (PAM)-agonist at the Type 1 Cholecystokinin Holoreceptor
Molecular Pharmacology
Molecular Medicine
Pharmacology
Utility of an "Allosteric Site-Impaired" M2 Muscarinic Acetylcholine Receptor as a Novel Construct for Validating Mechanisms of Action of Synthetic and Putative Endogenous Allosteric Modulators
Molecular Pharmacology
Molecular Medicine
Pharmacology
Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor Antagonists
Molecular Pharmacology
Molecular Medicine
Pharmacology
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