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Publications by Yuichi Sugiyama
Dose‐Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs
Clinical Pharmacology and Therapeutics
Pharmacology
PBPK Models for Evaluating Membrane Transporter Mediated DDIs: Current Capabilities, Case Studies, Future Opportunities and Recommendations
Clinical Pharmacology and Therapeutics
Pharmacology
Association Study of Genetic Polymorphisms of Drug Transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and Olmesartan Exposure
Journal of Human Genetics
Genetics
Physiologically Based Pharmacokinetic (PBPK) Modeling Analysis for Quantitative Prediction of Renal Transporter-Mediated Interactions Between Metformin and Cimetidine
CPT: Pharmacometrics and Systems Pharmacology
Modeling
Simulation
Cardiovascular Medicine
Pharmacology
Cardiology
A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
Drug Metabolism and Disposition
Pharmacology
Pharmaceutical Science
Comparison of Methods for Estimating Unbound Intracellular-To-Medium Concentration Ratios in Rat and Human Hepatocytes Using Statins
Drug Metabolism and Disposition
Pharmacology
Pharmaceutical Science
Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1a2- Madin-Darby Canine Kidney II: A Promising in Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
Drug Metabolism and Disposition
Pharmacology
Pharmaceutical Science
The Phenomenon of "Albumin-Mediated" Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of Thein Vivouptake Clearance From Thein Vitrouptake by Isolated Hepatocytes Using a "Facilitated-Dissociation" Model
Drug Metabolism and Disposition
Pharmacology
Pharmaceutical Science
Extrapolation of in Vivo Hepatic Clearance From in Vitro Uptake Clearance by Suspended Human Hepatocytes (IVIVE) for Anionic Drugs With High Binding to Human Albumin: Improvement of IVIVE by Considering the "Albumin-Mediated" Hepatic Uptake Mechanism Based on the Facilitated-Dissociation Model
Drug Metabolism and Disposition
Pharmacology
Pharmaceutical Science
Comparison of the Predictability of Human Hepatic Clearance for Organic Anion Transporting Polypeptide Substrate Drugs Between Different in Vitro–In Vivo Extrapolation Approaches
Journal of Pharmaceutical Sciences
Pharmaceutical Science
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