Discover open access scientific publications

Search, annotate, share and cite publications

Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)5-((4-((Morpholin-2-Ylmethyl)amino)-5-(Trifluoromethyl)pyridin-2-Yl)amino)pyrazine-2-Carbonitrile (CCT245737)

English

Crystal Structure and Hirshfeld Surface Analysis of 1-(4-Chlorophenyl)-2-{[5-(4-Chlorophenyl)-1,3,4-Oxadiazol-2-Yl]sulfanyl}ethanone

Acta Crystallographica Section E: Crystallographic Communications

Materials Science

Chemistry

Condensed Matter Physics

2017

English

Heterocycle–Heterocycle Strategies: (2-Nitrophenyl)isoxazole Precursors to 4-Aminoquinolines, 1h-Indoles, and Quinolin-4(1h)-Ones

Organic Letters

Biochemistry

Organic Chemistry

Theoretical Chemistry

Physical

2013

English

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Regulates the Stability and Function of GluA1 Α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid (AMPA) Receptor in Neurons

PLoS ONE

Multidisciplinary

2014

English

An .ALPHA.-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Antagonist and an N-Methyl-D-Aspartate (NMDA) Channel Blocker Synergistically Impair Spatial Memory in Rats.

Biological and Pharmaceutical Bulletin

Medicine

Pharmacology

Pharmaceutical Science

1998

English

KOtBu-Promoted Three-Component Coupling of Aldehydes and Alkynes: Highly Efficient Synthesis of 1-En-4-Yn-3-Ols and 2-En-4-Yn-1-Ols

English

Transport of NAD+ in Percoll-Purified Potato Tuber Mitochondria: Inhibition of NAD+ Influx and Efflux by N-4-Azido-2-Nitrophenyl-4-Aminobutyryl-3'-Nad+

English

Synthesis, Characterizations and Investigation of Electrochemical Behaviours of 4-[(2-Hydroxyphenylimino)methyl]benzene-1,3-Diol

E-Journal of Chemistry

2009

English

(S)-N-[1-(5-Benzylsulfanyl-1,3,4-Oxadiazol-2-Yl)-2-Phenylethyl]-4-Methylbenzenesulfonamide

Acta Crystallographica Section E Structure Reports Online

2011

English

Spiro Heterocyclic Compounds. IV. Synthesis of Spiro[oxindole-3,4'-(2',3'-Dihydro-4'h-Pyran)] and Spiro[oxindole-3,4'-(1',4'-Dihydropyridine)] Compounds.

Chemical and Pharmaceutical Bulletin

English

Amanote Research

Discover open access scientific publications

Search, annotate, share and cite publications

Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)5-((4-((Morpholin-2-Ylmethyl)amino)-5-(Trifluoromethyl)pyridin-2-Yl)amino)pyrazine-2-Carbonitrile (CCT245737)

Crystal Structure and Hirshfeld Surface Analysis of 1-(4-Chlorophenyl)-2-{[5-(4-Chlorophenyl)-1,3,4-Oxadiazol-2-Yl]sulfanyl}ethanone

Heterocycle–Heterocycle Strategies: (2-Nitrophenyl)isoxazole Precursors to 4-Aminoquinolines, 1h-Indoles, and Quinolin-4(1h)-Ones

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Regulates the Stability and Function of GluA1 Α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid (AMPA) Receptor in Neurons

An .ALPHA.-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Antagonist and an N-Methyl-D-Aspartate (NMDA) Channel Blocker Synergistically Impair Spatial Memory in Rats.

KOtBu-Promoted Three-Component Coupling of Aldehydes and Alkynes: Highly Efficient Synthesis of 1-En-4-Yn-3-Ols and 2-En-4-Yn-1-Ols

Transport of NAD+ in Percoll-Purified Potato Tuber Mitochondria: Inhibition of NAD+ Influx and Efflux by N-4-Azido-2-Nitrophenyl-4-Aminobutyryl-3'-Nad+

Synthesis, Characterizations and Investigation of Electrochemical Behaviours of 4-[(2-Hydroxyphenylimino)methyl]benzene-1,3-Diol

(S)-N-[1-(5-Benzylsulfanyl-1,3,4-Oxadiazol-2-Yl)-2-Phenylethyl]-4-Methylbenzenesulfonamide

Spiro Heterocyclic Compounds. IV. Synthesis of Spiro[oxindole-3,4'-(2',3'-Dihydro-4'h-Pyran)] and Spiro[oxindole-3,4'-(1',4'-Dihydropyridine)] Compounds.