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Discovery of (R)-6-(1-(8-Fluoro-6-(1-Methyl-1h-Pyrazol-4-Yl)-[1,2,4]triazolo[4,3-A]pyridin-3-Yl)ethyl)-3-(2-Methoxyethoxy)-1,6-Naphthyridin-5(6h)-One (AMG 337), a Potent and Selective Inhibitor of MET With High Unbound Target Coverage and Robust in Vivo Antitumor Activity

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2016

English

Comparative Study of the Cytotoxic Properties of Isatin-Containing Derivatives of 4-Thiazolidinone With Different Structure Toward Human Tumor Cells in Vitro

Studia Biologica

2014

English

Synthesis and Release of Steroids in Intestines From Cynomolgus Monkeys (Macaca Fascicularis)

English

Triplet State Dynamics in Poly(2,5-Pyridine Diyl)

Synthetic Metals

Mechanics of Materials

Alloys

Condensed Matter Physics

Mechanical Engineering

English

Syntheses and Biological Activities of Substance P Analogs Containing L- And D-Homoglutamine and L- And D-Pyrohomoglutamic Acid at Position 5 and 6

Bulletin of the Chemical Society of Japan

Chemistry

1987

English

On the Reaction of the Half Ester of 2-Methylpropylidene Malonic Acid With N-Bromosuccinimide. Preparation of Ethyl Methyl (E)-2-Bromo-2-Methylpropylidenemalonate.

Acta Chemica Scandinavica

1981

English

Rolling and Recrystallization Textures in 2-Nine, 3-Nine, 4-Nine and 5-Nine Al

Nippon Kinzoku Gakkaishi/Journal of the Japan Institute of Metals

Mechanics of Materials

Alloys

Materials Chemistry

Condensed Matter Physics

Metals

1967

English

A Stereoselective Approach to (Z)-1-Silyl-2-Aryl-1,3-Dienes From 4-(Phenylselanyl)But-1-Yne via Palladium-Catalyzed Silylstannylation and Selenoxide Elimination

English

Level Sets of Derivatives

Transactions of the American Mathematical Society

Mathematics

Applied Mathematics

1982

English

Harmonic Analysis of Vibrations of 4-Chloro-2-Fluroaniline: A Scaled Quantum Mechanical Approach

Oriental Journal of Chemistry

Biochemistry

Environmental Chemistry

Drug Discovery

Chemistry

2013

English

Amanote Research

Discover open access scientific publications

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Discovery of (R)-6-(1-(8-Fluoro-6-(1-Methyl-1h-Pyrazol-4-Yl)-[1,2,4]triazolo[4,3-A]pyridin-3-Yl)ethyl)-3-(2-Methoxyethoxy)-1,6-Naphthyridin-5(6h)-One (AMG 337), a Potent and Selective Inhibitor of MET With High Unbound Target Coverage and Robust in Vivo Antitumor Activity

Comparative Study of the Cytotoxic Properties of Isatin-Containing Derivatives of 4-Thiazolidinone With Different Structure Toward Human Tumor Cells in Vitro

Synthesis and Release of Steroids in Intestines From Cynomolgus Monkeys (Macaca Fascicularis)

Triplet State Dynamics in Poly(2,5-Pyridine Diyl)

Syntheses and Biological Activities of Substance P Analogs Containing L- And D-Homoglutamine and L- And D-Pyrohomoglutamic Acid at Position 5 and 6

On the Reaction of the Half Ester of 2-Methylpropylidene Malonic Acid With N-Bromosuccinimide. Preparation of Ethyl Methyl (E)-2-Bromo-2-Methylpropylidenemalonate.

Rolling and Recrystallization Textures in 2-Nine, 3-Nine, 4-Nine and 5-Nine Al

A Stereoselective Approach to (Z)-1-Silyl-2-Aryl-1,3-Dienes From 4-(Phenylselanyl)But-1-Yne via Palladium-Catalyzed Silylstannylation and Selenoxide Elimination

Level Sets of Derivatives

Harmonic Analysis of Vibrations of 4-Chloro-2-Fluroaniline: A Scaled Quantum Mechanical Approach