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Discovery of (R)-6-(1-(8-Fluoro-6-(1-Methyl-1h-Pyrazol-4-Yl)-[1,2,4]triazolo[4,3-A]pyridin-3-Yl)ethyl)-3-(2-Methoxyethoxy)-1,6-Naphthyridin-5(6h)-One (AMG 337), a Potent and Selective Inhibitor of MET With High Unbound Target Coverage and Robust in Vivo Antitumor Activity

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2016

English

Crystal Structure of [Cu(tmpen)](BF4)2{tmpen isN,N,N′,N′-tetrakis[(6-methylpyridin-2-yl)methyl]ethane-1,2-diamine}

Acta Crystallographica Section E: Crystallographic Communications

Materials Science

Chemistry

Condensed Matter Physics

2017

English

.ALPHA.-Bromo-.ALPHA.,.ALPHA.-difluoroallyl Derivatives as Synthetic Intermediate. Nucleophilic Substitution of .ALPHA.-Bromo-.ALPHA.,.ALPHA.-difluoroallyl Derivatives in the Presence of Palladium Catalysts.

Chemical and Pharmaceutical Bulletin

English

Synthesis of 6-Methyl-9-N-Propyldibenzothiophene-4-Ol. Quarterly Technical Progress Report No. 4, April 25--July 25, 1991

1991

English

Stereoselective Suzuki Coupling Reaction of an Α-Bromo-Α-Fluoro-Β-Lactam

Synlett

Organic Chemistry

2014

English

Solid-Phase Spectrophotometric Determination of Cobalt(II) in Tap Water and Beverages Using 2-(5-Bromo-2-Pyridylazo)-5-(N-Propyl-N-(3-Sulfopropyl)amino)phenol After Preconcentration as the 1-(2-Pyridylazo)-2-Naphthol Complex.

Analytical Sciences

Analytical Chemistry

1998

English

Convenient Synthesis of Some Methyl-N-[2-(6-Oxo-3-P-Tolyl-5,6-Dihydro-4h-Pyridazin-1-Yl)-Acetamide]alkanoates

2008

English

Synthesis of 4-(2h-[1,2,4]-Triazol-5-Ylsulfanyl)-1,2-Dihydropyrazol-3-One via Ring-Switching Hydrazinolysis of 5-Ethoxymethylidenethiazolo [3,2-B][1,2,4]triazol-6-One

MolBank

Biochemistry

Organic Chemistry

Theoretical Chemistry

Physical

2018

English

Studies on Diazabenzobicyclo [3.3.1] Nonane System. IV. Synthesis of 1, 2, 3, 4, 5, 6-Hexahydro-1, 5-Methanobenzo [E] [1, 3] Diazocine Derivatives

Chemical and Pharmaceutical Bulletin

English

Changes in the TRMM Version-5 and Version-6 Precipitation Radar Products Due to Orbit Boost

Journal of the Meteorological Society of Japan

Atmospheric Science

2009

English

Amanote Research

Discover open access scientific publications

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Discovery of (R)-6-(1-(8-Fluoro-6-(1-Methyl-1h-Pyrazol-4-Yl)-[1,2,4]triazolo[4,3-A]pyridin-3-Yl)ethyl)-3-(2-Methoxyethoxy)-1,6-Naphthyridin-5(6h)-One (AMG 337), a Potent and Selective Inhibitor of MET With High Unbound Target Coverage and Robust in Vivo Antitumor Activity

Crystal Structure of [Cu(tmpen)](BF4)2{tmpen isN,N,N′,N′-tetrakis[(6-methylpyridin-2-yl)methyl]ethane-1,2-diamine}

.ALPHA.-Bromo-.ALPHA.,.ALPHA.-difluoroallyl Derivatives as Synthetic Intermediate. Nucleophilic Substitution of .ALPHA.-Bromo-.ALPHA.,.ALPHA.-difluoroallyl Derivatives in the Presence of Palladium Catalysts.

Synthesis of 6-Methyl-9-N-Propyldibenzothiophene-4-Ol. Quarterly Technical Progress Report No. 4, April 25--July 25, 1991

Stereoselective Suzuki Coupling Reaction of an Α-Bromo-Α-Fluoro-Β-Lactam

Solid-Phase Spectrophotometric Determination of Cobalt(II) in Tap Water and Beverages Using 2-(5-Bromo-2-Pyridylazo)-5-(N-Propyl-N-(3-Sulfopropyl)amino)phenol After Preconcentration as the 1-(2-Pyridylazo)-2-Naphthol Complex.

Convenient Synthesis of Some Methyl-N-[2-(6-Oxo-3-P-Tolyl-5,6-Dihydro-4h-Pyridazin-1-Yl)-Acetamide]alkanoates

Synthesis of 4-(2h-[1,2,4]-Triazol-5-Ylsulfanyl)-1,2-Dihydropyrazol-3-One via Ring-Switching Hydrazinolysis of 5-Ethoxymethylidenethiazolo [3,2-B][1,2,4]triazol-6-One

Studies on Diazabenzobicyclo [3.3.1] Nonane System. IV. Synthesis of 1, 2, 3, 4, 5, 6-Hexahydro-1, 5-Methanobenzo [E] [1, 3] Diazocine Derivatives

Changes in the TRMM Version-5 and Version-6 Precipitation Radar Products Due to Orbit Boost