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Publications by Aleem Gangjee

Structure–Activity Relationship and in Vitro and in Vivo Evaluation of the Potent Cytotoxic Anti-Microtubule AgentN-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium Chloride and Its Analogues as Antitumor Agents

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2013

English

Discovery of 5-Substituted Pyrrolo[2,3-D]pyrimidine Antifolates as Dual-Acting Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase in De Novo Purine Nucleotide Biosynthesis: Implications of Inhibiting 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase to AMPK Activation and Antitumor Activity

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2013

English

Synthesis and Biological Activity of 5-Chloro-N4-Substituted Phenyl-9h-Pyrimido[4,5-B]indole-2,4-Diamines as Vascular Endothelial Growth Factor Receptor-2 Inhibitors and Antiangiogenic Agents

Bioorganic and Medicinal Chemistry

Clinical Biochemistry

Pharmaceutical Science

Drug Discovery

2013

English

Synthesis of Classical, Four-Carbon Bridged 5-Substituted Furo[2,3-D]pyrimidine and 6-Substituted Pyrrolo[2,3-D]pyrimidine Analogues as Antifolates1

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2005

English

Design, Synthesis, and X-Ray Crystal Structures of 2,4-Diaminofuro[2,3-D]pyrimidines as Multireceptor Tyrosine Kinase and Dihydrofolate Reductase Inhibitors

Bioorganic and Medicinal Chemistry

Clinical Biochemistry

Pharmaceutical Science

Drug Discovery

2009

English

Synthesis and Evaluation of a Classical 2,4-Diamino-5-Substituted-Furo[2,3-D]pyrimidine and a 2-Amino-4-Oxo-6-Substituted-Pyrrolo[2,3-D]pyrimidine as Antifolates

Bioorganic and Medicinal Chemistry

Clinical Biochemistry

Pharmaceutical Science

Drug Discovery

2006

English

Amanote Research

Discover open access scientific publications

Search, annotate, share and cite publications

Publications by Aleem Gangjee

Structure–Activity Relationship and in Vitro and in Vivo Evaluation of the Potent Cytotoxic Anti-Microtubule AgentN-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium Chloride and Its Analogues as Antitumor Agents

Synthesis and Biological Activity of 5-Chloro-N4-Substituted Phenyl-9h-Pyrimido[4,5-B]indole-2,4-Diamines as Vascular Endothelial Growth Factor Receptor-2 Inhibitors and Antiangiogenic Agents

Synthesis of Classical, Four-Carbon Bridged 5-Substituted Furo[2,3-D]pyrimidine and 6-Substituted Pyrrolo[2,3-D]pyrimidine Analogues as Antifolates1

Design, Synthesis, and X-Ray Crystal Structures of 2,4-Diaminofuro[2,3-D]pyrimidines as Multireceptor Tyrosine Kinase and Dihydrofolate Reductase Inhibitors

Synthesis and Evaluation of a Classical 2,4-Diamino-5-Substituted-Furo[2,3-D]pyrimidine and a 2-Amino-4-Oxo-6-Substituted-Pyrrolo[2,3-D]pyrimidine as Antifolates