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Publications in Molecular Medicine

Structure–Activity Relationships of Peptides Incorporating a Bioactive Reverse-Turn Heterocycle at the Melanocortin Receptors: Identification of a 5800-Fold Mouse Melanocortin-3 Receptor (mMC3R) Selective Antagonist/Partial Agonist Versus the Mouse Melanocortin-4 Receptor (mMC4R)

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2013English

Structure–Activity Relationship and in Vitro and in Vivo Evaluation of the Potent Cytotoxic Anti-Microtubule AgentN-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium Chloride and Its Analogues as Antitumor Agents

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2013English

A High-Throughput Screening Identifies microRNA Inhibitors That Influence Neuronal Maintenance and/or Response to Oxidative Stress

Molecular Therapy - Nucleic Acids
Drug DiscoveryMolecular Medicine
2019English

Efficient Generation of Functional Dopaminergic Neurons From Human Induced Pluripotent Stem Cells Under Defined Conditions

Stem Cells
MedicineMolecular MedicineDevelopmental BiologyCell Biology
2010English

Use of Heterologous Vesiculovirus G Proteins Circumvents the Humoral Anti-Envelope Immunity in Lentivector Based in Vivo Gene Delivery

Molecular Therapy - Nucleic Acids
Drug DiscoveryMolecular Medicine
2019English

Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3).

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2018English

Concise Review: Stem Cells in Pancreatic Cancer: From Concept to Translation

Stem Cells
MedicineMolecular MedicineDevelopmental BiologyCell Biology
2015English

Targeting Translation Termination Machinery With Antisense Oligonucleotides for Diseases Caused by Nonsense Mutations

Nucleic Acid Therapeutics
BiochemistryMolecular MedicineDrug DiscoveryGeneticsMolecular Biology
2019English

Identification and Characterization of Small Molecules as Potent and Specific EPAC2 Antagonists

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2013English

Removal of the 26-Methyl Group From 19-Nor-1α,25-Dihydroxyvitamin D3Markedly Reduces in Vivo Calcemic Activity Without Altering in Vitro VDR Binding, HL-60 Cell Differentiation, and Transcription

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2010English

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