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Biodegradation of Nitro-Substituted Explosives 2,4,6-Trinitrotoluene, Hexahydro-1,3,5-Trinitro-1,3,5-Triazine, and Octahydro-1,3,5,7-Tetranitro-1,3,5-Tetrazocine by a Phytosymbiotic Methylobacterium Sp. Associated With Poplar Tissues (Populus Deltoides X Nigra DN34)

Applied and Environmental Microbiology

Applied Microbiology

English

Part 2: Efficient Strategies for the Construction of Variably Substituted Bicyclo[5.3.1]undecenones (AB-taxane Ring Systems) and Their Conversion to Tricyclo[9.3.1.03,8]pentadecenones (ABC Taxane Ring Systems) and Bicyclo[2.2.2]octanones

Canadian Journal of Chemistry

English

A Computational Study on P and S Modes of Metal Ion Binding to Heteroaromatics (CH)5-mXm and (CH)6-mXm (X = N and P): Contrasting Preferences Between Nitrogen- And Phosphorous-Substituted Rings

English

Discovery of 5-Substituted Pyrrolo[2,3-D]pyrimidine Antifolates as Dual-Acting Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase in De Novo Purine Nucleotide Biosynthesis: Implications of Inhibiting 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase to AMPK Activation and Antitumor Activity

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2013

English

Role of the Ligand and of the Size and Flexibility of the Palladium-Ancillary Ligand Cycle on the Reactivity of Substituted Alkynes Toward Palladium(0) Complexes Bearing Potentially Terdentate Nitrogen-Sulfur-Nitrogen or Nitrogen-Nitrogen-Nitrogen Ligands: Kinetic and Structural Study

English

Synthesis, Properties, and NAD+-NADH-Type Redox Ability of 14-Substituted 1, 3-Dimethyl-5, 10-Methanocycloundeca[4, 5]pyrrolo[2, 3-D]pyrimidine-2, 4(1, 3h)-Dionylium Tetrafluoroborates and Their Hydride Adducts

English

Discovery of [Cis-3-({(5r)5-[(7-Fluoro-1,1-Dimethyl-2,3-Dihydro1Hinden-5-Yl)carbamoyl]-2-Methoxy-7,8-Dihydro-1,6-Naphthyridin-6(5H)yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor T Inverse Agonist

English

The Studies on the Structure-Activity Relationship of Allyl Substituted Oxopyrimidines Searching for the Novel Antagonist or Agonist of Barbiturates to the Sleep Mechanism Based on the Uridine Receptor Theory &Mdash;Barbituric Acid to Uridine (Part I)1)—

Yakugaku Zasshi

Pharmacology

Pharmaceutical Science

2005

English

Design and Synthesis of Novel Derivatives of the Muscarinic Agonist Tetra(ethylene Glycol)(3-Methoxy-1, 2, 5-Thiadiazol-4-Yl) [3-(1-Methyl-1, 2, 5, 6-Tetrahydropyrid-3-Yl)-1, 2, 5-Thiadiazol-4-Yl] Ether (CDD-0304): Effects of Structural Modifications on the Binding and Activity at Muscarinic Receptor Subtypes and Chimeras

English

Thermal and Metal-Catalyzed Cyclization of 1-Substituted 3, 5-Dien-1-Ynes via a [1, 7]-Hydrogen Shift: Development of a Tandem Aldol Condensation-Dehydration and Aromatization Catalysis Between 3-En-1-Yn-5-Al Units and Cyclic Ketones

English

Amanote Research

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Biodegradation of Nitro-Substituted Explosives 2,4,6-Trinitrotoluene, Hexahydro-1,3,5-Trinitro-1,3,5-Triazine, and Octahydro-1,3,5,7-Tetranitro-1,3,5-Tetrazocine by a Phytosymbiotic Methylobacterium Sp. Associated With Poplar Tissues (Populus Deltoides X Nigra DN34)

Part 2: Efficient Strategies for the Construction of Variably Substituted Bicyclo[5.3.1]undecenones (AB-taxane Ring Systems) and Their Conversion to Tricyclo[9.3.1.03,8]pentadecenones (ABC Taxane Ring Systems) and Bicyclo[2.2.2]octanones

A Computational Study on P and S Modes of Metal Ion Binding to Heteroaromatics (CH)5-mXm and (CH)6-mXm (X = N and P): Contrasting Preferences Between Nitrogen- And Phosphorous-Substituted Rings

Role of the Ligand and of the Size and Flexibility of the Palladium-Ancillary Ligand Cycle on the Reactivity of Substituted Alkynes Toward Palladium(0) Complexes Bearing Potentially Terdentate Nitrogen-Sulfur-Nitrogen or Nitrogen-Nitrogen-Nitrogen Ligands: Kinetic and Structural Study

Synthesis, Properties, and NAD+-NADH-Type Redox Ability of 14-Substituted 1, 3-Dimethyl-5, 10-Methanocycloundeca[4, 5]pyrrolo[2, 3-D]pyrimidine-2, 4(1, 3h)-Dionylium Tetrafluoroborates and Their Hydride Adducts

Discovery of [Cis-3-({(5r)5-[(7-Fluoro-1,1-Dimethyl-2,3-Dihydro1Hinden-5-Yl)carbamoyl]-2-Methoxy-7,8-Dihydro-1,6-Naphthyridin-6(5H)yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor T Inverse Agonist

The Studies on the Structure-Activity Relationship of Allyl Substituted Oxopyrimidines Searching for the Novel Antagonist or Agonist of Barbiturates to the Sleep Mechanism Based on the Uridine Receptor Theory &Mdash;Barbituric Acid to Uridine (Part I)1)&mdash;

Thermal and Metal-Catalyzed Cyclization of 1-Substituted 3, 5-Dien-1-Ynes via a [1, 7]-Hydrogen Shift: Development of a Tandem Aldol Condensation-Dehydration and Aromatization Catalysis Between 3-En-1-Yn-5-Al Units and Cyclic Ketones

The Studies on the Structure-Activity Relationship of Allyl Substituted Oxopyrimidines Searching for the Novel Antagonist or Agonist of Barbiturates to the Sleep Mechanism Based on the Uridine Receptor Theory &Mdash;Barbituric Acid to Uridine (Part I)1)—